BDBM50225103 CHEMBL249372::isopropyl ((S)-2-(2-(1-(dimethylamino)-2-methyl-1-oxopropan-2-yl)-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrol-4-yl)propylamino)(3-(pyridin-4-yl)pyrrolidin-1-yl)methylenecarbamate

SMILES CC(C)OC(=O)N=C(NC[C@@H](C)c1c([nH]c2sc(cc12)C(C)(C)C(=O)N(C)C)-c1cc(C)cc(C)c1)N1CCC(C1)c1ccncc1

InChI Key InChIKey=QBFCIBUPOVSOBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225103   

TargetGonadotropin-releasing hormone receptor(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225103(isopropyl ((S)-2-(2-(1-(dimethylamino)-2-methyl-1-...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225103(isopropyl ((S)-2-(2-(1-(dimethylamino)-2-methyl-1-...)
Affinity DataIC50: 244nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225103(isopropyl ((S)-2-(2-(1-(dimethylamino)-2-methyl-1-...)
Affinity DataIC50: 452nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pituitary cells assessed as inhibition of GnRH stimulated LH release afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed