BDBM50225602 (4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-yl)((3R,4S)-4-(4-chlorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)methanone::CHEMBL246631

SMILES Clc1ccc(cc1)[C@H]1CN(C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1)C1CCOCC1

InChI Key InChIKey=KHEXESSWWLGQFI-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225602   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50225602((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...)
Affinity DataKi:  29nMAssay Description:Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50225602((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to MC5RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed