BDBM50225610 (4-(1-((4-(dimethylamino)benzylamino)methyl)cyclohexyl)piperazin-1-yl)((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-3-yl)methanone::CHEMBL401488

SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(cc2)N(C)C)CCCCC1

InChI Key InChIKey=DZVVHXRWRSSYLZ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225610   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50225610((4-(1-((4-(dimethylamino)benzylamino)methyl)cycloh...)
Affinity DataKi:  65nMAssay Description:Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50225610((4-(1-((4-(dimethylamino)benzylamino)methyl)cycloh...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at MC4R assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed