BDBM50225816 (E)-3-(8-morpholino-4-oxo-7-(2-phenylethynyl)-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)benzonitrile::CHEMBL236467

SMILES O=C1CC(=Nc2cc(N3CCOCC3)c(cc2N1)C#Cc1ccccc1)c1cccc(c1)C#N

InChI Key InChIKey=FGNZXALQOFFQIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225816   

TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50225816((E)-3-(8-morpholino-4-oxo-7-(2-phenylethynyl)-4,5-...)
Affinity DataIC50: 378nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed