BDBM50226373 1-(4-Amino-phenyl)-3-(3-benzo[1,3]dioxol-5-yl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-urea::CHEMBL253429

SMILES Nc1ccc(NC(=O)Nc2cccc3-c4[nH]nc(c4C(=O)c23)-c2ccc3OCOc3c2)cc1

InChI Key InChIKey=ZXNFACJZSMSYCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226373   

TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50226373(1-(4-Amino-phenyl)-3-(3-benzo[1,3]dioxol-5-yl-4-ox...)
Affinity DataIC50: 214nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50226373(1-(4-Amino-phenyl)-3-(3-benzo[1,3]dioxol-5-yl-4-ox...)
Affinity DataIC50: 380nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed