BDBM50226444 6-(3-(1H-pyrrol-2-yl)phenethyl)-2-amino-3-methylpyrimidin-4(3H)-one::CHEMBL396830

SMILES Cn1c(N)nc(CCc2cccc(c2)-c2ccc[nH]2)cc1=O

InChI Key InChIKey=FIWKGPGHVQEJNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226444   

TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226444(6-(3-(1H-pyrrol-2-yl)phenethyl)-2-amino-3-methylpy...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of BACE1 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226444(6-(3-(1H-pyrrol-2-yl)phenethyl)-2-amino-3-methylpy...)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226444(6-(3-(1H-pyrrol-2-yl)phenethyl)-2-amino-3-methylpy...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of BACE1 by IGEN assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed