BDBM50226638 CHEMBL237022::N-(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethyl){[3-(nitrooxy)propyl]amino}carboxamide

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CCNC(=O)NCCCO[N+]([O-])=O)c2c1

InChI Key InChIKey=SFHUMPQJFLDISM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226638   

TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226638(CHEMBL237022 | N-(2-{1-[(4-chlorophenyl)carbonyl]-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226638(CHEMBL237022 | N-(2-{1-[(4-chlorophenyl)carbonyl]-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed