BDBM50226652 4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitrooxy)-propyl]sulfonyl}-amino)ethyl]indolyl ketone::CHEMBL237207

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CCNS(=O)(=O)CCCO[N+]([O-])=O)c2c1

InChI Key InChIKey=OGLOZKAFGOPOJZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50226652   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed