BDBM50226656 CHEMBL393680::N-{1,1-bis[(nitrooxy)methyl]-2-(nitrooxy)ethyl}-2-{1-[(4-chlorophenyl)-arbonyl]-5-methoxy-2-methylindol-3-yl}acetamide

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(CO[N+]([O-])=O)(CO[N+]([O-])=O)CO[N+]([O-])=O)c2c1

InChI Key InChIKey=IBMWAPWIRVLFOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226656   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226656(CHEMBL393680 | N-{1,1-bis[(nitrooxy)methyl]-2-(nit...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed