BDBM50228420 CHEMBL391968::di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-2-[(4-guanidino)phenyl]ethanephosphonate

SMILES [#6]-[#6](=O)-[#7]-c1ccc(-[#8]P(=O)([#8]-c2ccc(-[#7]-[#6](-[#6])=O)cc2)[#6](-[#6]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)cc1

InChI Key InChIKey=WHOCSXXAQICVLG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228420   

TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228420(di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228420(di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228420(di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228420(di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228420(di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed