BDBM50228755 ((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-methyl}-3-oxo-1-phenylmethanesulfonyl-piperazin-2-yl)-acetic acid methyl ester::CHEMBL272961::methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-ylamino)-2-oxoethyl)-3-oxopiperazin-2-yl)acetate

SMILES COC(=O)C[C@H]1C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)c2nccs2)CCN1S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=ABNSZFKXNPQIGT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228755   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228755BDBM50228755(methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guani...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228755BDBM50228755(methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guani...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228755BDBM50228755(methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guani...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against serine protease thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228755BDBM50228755(methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guani...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed