BDBM50228910 2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphenyl-4-yl]-1-[2-(4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-ethanone::CHEMBL402167

SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Cc1ccc(cc1)-c1ccccc1CN1CC[C@H](O)C1)C(F)(F)F

InChI Key InChIKey=MHMSYXOVNQSRJW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228910   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228910(2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphen...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228910(2-[2'-((S)-3-hydroxy-pyrrolidin-1-ylmethyl)-biphen...)
Affinity DataKi: >6.30E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed