BDBM50229101 5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N,2-dimethyl-N-(2-(methylamino)ethyl)benzamide::CHEMBL254269

SMILES CNCCN(C)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C

InChI Key InChIKey=KOCGMVOWSRIEAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229101   

TargetHigh affinity nerve growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50229101(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...)
Affinity DataIC50: 31nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50229101(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50229101(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50229101(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed