BDBM50229221 2-(4'-chloro-biphenyl-4-yl)-N-(4-trifluoromethanesulfonylamino-benzyl)-acetamide::CHEMBL253923

SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C

InChI Key InChIKey=DCTZZTABOYYDMY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229221   

TargetBombesin receptor subtype-3(Human)
Eotvos Lorand University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229221BDBM50229221(CHEMBL6102759)
Affinity DataIC50: 1.10nMAssay Description:Agonist activity at human recombinant beta2 receptor assessed as cAMP accumulation by radioimmunoassay and cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed
TargetGastrin-releasing peptide receptor(Human)
Eotvos Lorand University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229221BDBM50229221(CHEMBL6102759)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details ArticlePubMed