BDBM50230420 CHEMBL4090083

SMILES NP(=O)(OCCCCOc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)N(CCCl)CCCl

InChI Key InChIKey=KAQHUJGJYUUQSI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50230420   

TargetEpidermal growth factor receptor(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230420BDBM50230420(CHEMBL4090083)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230420BDBM50230420(CHEMBL4090083)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230420BDBM50230420(CHEMBL4090083)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230420BDBM50230420(CHEMBL4090083)
Affinity DataIC50: 82nMAssay Description:Inhibition of gamma-secretase mediated amyloid beta-40 production in HEK293 cells by whole cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed