BDBM50231812 CHEMBL4103961::US11725000, Compound 58

SMILES COC(=O)c1ccccc1-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=IARSPZQLAVMSOT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231812   

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing

US Patent
LigandPNGBDBM50231812(CHEMBL4103961 | US11725000, Compound 58)
Affinity DataEC50: <1.00E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Human)
National Institute of Biological Sciences, Beijing

US Patent
LigandPNGBDBM50231812(CHEMBL4103961 | US11725000, Compound 58)
Affinity DataEC50:  7.03E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed