BDBM50232448 CHEMBL4072625

SMILES CC(=O)N1CCN(CC1)c1cccc(c1)-c1cc(-c2ccnn2C2COC2)c2c(N)ncnn12

InChI Key InChIKey=FMZCAHXYZKLKNJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232448   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50232448(CHEMBL4072625)Copy SMILESCopy InChI

Affinity DataIC50:  6.60nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50232448(CHEMBL4072625)Copy SMILESCopy InChI

Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL