BDBM50232581 CHEMBL4096151

SMILES CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)N[C@H]4CC[C@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C

InChI Key InChIKey=CKAZLPSHMQDEHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232581   

TargetSerine/threonine-protein kinase PLK1(Human)
Takeda California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232581BDBM50232581(CHEMBL4096151)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human FLAG-tagged PLK1 expressed in baculovirus infected sf21 cells using Biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed