BDBM50232780 CHEMBL4061176

SMILES O=C1/C(=C/c2c[nH]c3nc(Cl)ccc23)Oc2c1ccc(O)c2CN1CCNCC1

InChI Key InChIKey=DMSYFHDBYSACBT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232780   

TargetSerine/threonine-protein kinase pim-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232780BDBM50232780(CHEMBL4061176)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM3 (1 to 326 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232780BDBM50232780(CHEMBL4061176)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PIM1 (1 to 313 end residues) expressed in baculovirus infected sf21 cells using S6K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232780BDBM50232780(CHEMBL4061176)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232780BDBM50232780(CHEMBL4061176)
Affinity DataIC50: 140nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed