BDBM50233156 CHEMBL4070321::US11124490, Compound 26a

SMILES CS(=O)(=O)N(C(=O)c1cc(NN2CCOCC2)c(Cl)cc1Cl)c1cc(F)c(F)c(F)c1

InChI Key InChIKey=BLDKLQWNOHNECW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233156   

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50233156(CHEMBL4070321 | US11124490, Compound 26a)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetAutotaxin(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50233156(CHEMBL4070321 | US11124490, Compound 26a)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details Article
PubMed