BDBM50233720 CHEMBL254909::N-(4-(4-acetylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-4-cyano-1H-pyrrole-2-carboxamide

SMILES CC(=O)N1CCN(c2ccc(NC(=O)c3cc(C#N)c[nH]3)c(N3CCC(C)CC3)c2)CC1

InChI Key InChIKey=QGPHKAQQVJRELW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233720   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233720BDBM50233720(N-(4-(4-acetylpiperazin-1-yl)-2-(4-methylpiperidin...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed