BDBM50233956 CHEMBL4075011

SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCNC(=O)CCc1cn(CCCCN2C[C@@H]3C[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N3)nn1

InChI Key InChIKey=YUFZLCHTKCDKMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233956   

TargetIntegrin alpha-V/beta-3(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50233956(CHEMBL4075011)
Affinity DataIC50: 1.20nMAssay Description:Displacement of biotinylated vitronectin from recombinant human integrin alphaVbeta3 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50233956(CHEMBL4075011)
Affinity DataIC50: 31nMAssay Description:Displacement of biotinylated fibronectin from recombinant human integrin alpha5beta1 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50233956(CHEMBL4075011)
Affinity DataIC50: 500nMAssay Description:Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed