BDBM50234044 CHEMBL4102416::US9765018, Example 145

SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2cccc3CCCc23)c(NC(=O)Nc2ccc(C)cc2)c1

InChI Key InChIKey=VGSHITYYMFAFSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234044   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50234044(US9765018, Example 145 | CHEMBL4102416)
Affinity DataIC50: 280nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production preincubated with cells followed by IFN-g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50234044(US9765018, Example 145 | CHEMBL4102416)
Affinity DataIC50: 1.59E+3nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
US Patent