BDBM50234084 CHEMBL4091953

SMILES Cc1ccc(NC(=O)c2cccc3OCCOc23)cc1NC(=O)c1ccc2nc(OCCN3CCCC3)ccc2c1

InChI Key InChIKey=BQURSSYYGUBULA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50234084   

TargetHeat shock factor protein 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234084(CHEMBL4091953)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPirin(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234084(CHEMBL4091953)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 6-amino-9-(2-((4-((2-((6-((5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)carbamoyl)quinolin-2-yl)oxy)ethyl)amino)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeat shock factor protein 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234084(CHEMBL4091953)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed