BDBM50234090 CHEMBL4069552::US9701664, Example 2

SMILES Cc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2ccncc2c1

InChI Key InChIKey=ZQOBGHCKTIESSE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50234090   

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50234090BDBM50234090(CHEMBL4069552 | US9701664, Example 2)
Affinity DataIC50: 25nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50234090BDBM50234090(CHEMBL4069552 | US9701664, Example 2)
Affinity DataIC50: 51nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50234090BDBM50234090(CHEMBL4069552 | US9701664, Example 2)
Affinity DataIC50: 51nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2019
Entry Details Article
PubMed