BDBM50234679 CHEMBL4087286

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(cc1)C(C)C

InChI Key InChIKey=RBBJXDWOGDHMSP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234679   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50234679(CHEMBL4087286)
Affinity DataKi:  4.40E+4nMAssay Description:Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21(DE3) measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2019
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50234679(CHEMBL4087286)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of 5'--FAM-LTFEHYWAQLTS peptide binding to N-terminal domain human MDMX (1 to 134 residues) measured after 15 mins by fluorescence polariz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2019
Entry Details Article
PubMed