BDBM50234835 CHEMBL4078405

SMILES Cc1cc(C)cc(c1)N(CCC(O)=O)C(=O)c1ccc2n(C)c(CNc3ccc(cc3F)C(N)=N)nc2c1

InChI Key InChIKey=YGQHCIWNKVUVCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234835   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234835(CHEMBL4078405)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed