BDBM50234840 CHEMBL4095408

SMILES Cc1cccc(N(CCC(O)=O)C(=O)c2ccc3n(C)c(CNc4ccc(cc4F)C(N)=N)nc3c2)c1C

InChI Key InChIKey=GJBKRIOYAQUYEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234840   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234840(CHEMBL4095408)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed