BDBM50234842 CHEMBL3740791

SMILES Cc1ccnc(c1)N(CCC(O)=O)C(=O)c1ccc2n(C)c(CNc3ccc(cc3F)C(N)=N)nc2c1

InChI Key InChIKey=JTBYHRPAZBVRFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234842   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234842(CHEMBL3740791)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50234842(CHEMBL3740791)
Affinity DataIC50: 24nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed