BDBM50234940 CHEMBL4101756

SMILES Cn1ncc(Nc2ccccc2CN)c(Cl)c1=O

InChI Key InChIKey=OHVGMQWGTYKZJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234940   

TargetNucleosome-remodeling factor subunit BPTF(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50234940(CHEMBL4101756)
Affinity DataIC50: 220nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234940(CHEMBL4101756)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2019
Entry Details Article
PubMed