BDBM50234979 CHEMBL4072186

SMILES CC(C)(C)CNC(=O)C[C@H](NC(=O)N1CCN(CC1)C(=O)c1ccc(F)cc1)C(=O)N[C@@H](CCc1ccccc1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=NDNXUVMUMGSZKO-ACHIHNKUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234979   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50234979(CHEMBL4072186)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed