BDBM50235563 CHEMBL254907::N1-(4-(6-(2-(dimethylamino)ethoxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-4-yloxy)-3-fluorophenyl)-N3-(4-fluorophenyl)malonamide

SMILES CN(C)CCOc1cn2ncnc(Oc3ccc(NC(=O)CC(=O)Nc4ccc(F)cc4)cc3F)c2c1C

InChI Key InChIKey=HWOXQSUVADVKLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235563   

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50235563(CHEMBL254907 | N1-(4-(6-(2-(dimethylamino)ethoxy)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50235563(CHEMBL254907 | N1-(4-(6-(2-(dimethylamino)ethoxy)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed