BDBM50236270 1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-6-(trifluoromethyl)phenyl)urea::CHEMBL401860

SMILES COc1ccc(cc1)-c1oc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2c(F)cccc2C(F)(F)F)cc1

InChI Key InChIKey=OWBPDWHZXAEGMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236270   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236270(1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant TIE2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50236270(1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed