BDBM50236966 CHEMBL4070091

SMILES COc1ccccc1N1CCN(CCCC(=O)Nc2ccn3ncc(C#N)c3c2)CC1

InChI Key InChIKey=VDIKOHJQRNCQAT-UHFFFAOYSA-N

Data  6 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50236966   

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]spiperone from human Dopamine D4 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from human Dopamine D3 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  380nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataKi:  860nMAssay Description:Displacement of [3H]SCH23390 from human Dopamine D1 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human Dopamine D2S receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50236966(CHEMBL4070091)
Affinity DataEC50:  42nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed