BDBM50237165 CHEMBL4098859

SMILES CCCN(CCCCOc1ccn2ncc(\C=N/O)c2c1)[C@H]1CCc2c(O)cccc2C1

InChI Key InChIKey=MWAPGIGSNBMUAD-UHFFFAOYSA-N

Data  6 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50237165   

TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoB ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  0.590nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  0.960nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at ARMS2-PK2 tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin-2 recru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]spiperone from human Dopamine D4 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2L receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  12nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataEC50:  13nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander University Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50237165(CHEMBL4098859)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]SCH23390 from human Dopamine D1 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed