BDBM50237999 CHEMBL4064834

SMILES Cc1cc2oc(=O)[nH]c2cc1Cl

InChI Key InChIKey=ORIHCLDAKSYERG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237999   

TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)
Affinity DataIC50: 631nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using L-kynurenine as substrate measured after 20 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of rat KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed