BDBM50238001 CHEMBL4060545

SMILES OC(=O)CCn1ncc2ccc(Cl)cc12

InChI Key InChIKey=UVDXMZQBAUASHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238001   

TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238001(CHEMBL4060545)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238001(CHEMBL4060545)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using L-kynurenine as substrate measured after 20 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed