BDBM50239276 3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triazole::CHEMBL428429

SMILES Cn1c(nnc1C12CC3CC(CC(C3)C1)C2)-c1ccccc1

InChI Key

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50239276   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 37nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 109nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 109nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 109nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed