BDBM50239363 CHEMBL4094351
SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)Nc4c(OC\C=C\CO2)c3)n2ncc(C#N)c2n1
InChI Key InChIKey=SABLEOBBNNRHAD-WNJMFGOSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50239363
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of GAL4 DNA binding domain fused PLZF BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKd: 6.5nMAssay Description:Binding affinity to Mcl1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...More data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor measured by inhibition of positive chronotropic effect of isoproterenolin in isolated...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Bcl6 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair