BDBM50239487 CHEMBL4089619
SMILES CC(C)Oc1cc2c(O[C@@H]3CCCNC3)nccc2cc1C(N)=O
InChI Key InChIKey=IGHCPQNSSZGPEV-CYBMUJFWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50239487
Affinity DataIC50: 121nMAssay Description:Inhibition of N-terminal His6-tagged human full length IRAK4 preincubated for 20 mins followed by biotinylated-AGAGRDKYKTLRQIR substrate addition in ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as reduction in R848-stimulated TNF alpha production after 3 hrsMore data for this Ligand-Target Pair