BDBM50239787 CHEMBL4094143

SMILES COc1ccc2sc(cc2c1)C(=O)NCc1cccc(F)c1

InChI Key InChIKey=RADHARZXGFWSKO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239787   

TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of S6 kinase expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1/CLK4(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239787(CHEMBL4094143)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of HDAC1 expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed