BDBM50239868 CHEMBL4097764

SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cccnc2)c1

InChI Key InChIKey=PSWMJOPGLAUUCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239868   

TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50:  180nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed