BDBM50240176 CHEMBL4092500::US9962398, Compound MST-145

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2cc(ccc2Cl)[N+]([O-])=O)cc1

InChI Key InChIKey=CNJFJOJOMZLMDA-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240176   

TargetCarbonic anhydrase 2(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  0.940nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  0.940nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  6.10nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  6.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  8.20nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  307nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
Welichem Biotech

US Patent
LigandPNGBDBM50240176(CHEMBL4092500 | US9962398, Compound MST-145)
Affinity DataKi:  307nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stoppe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details Article
PubMed