BDBM50240283 CHEMBL4082930

SMILES F[C@@H]1CN2CCC[C@]2(CNc2cc(F)c(cc2Cl)S(=O)(=O)Nc2nccs2)C1

InChI Key InChIKey=CYADIXZUNKDWSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240283   

TargetSodium channel protein type 9 subunit alpha(Human)
Department of Discovery Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50240283(CHEMBL4082930)
Affinity DataIC50: 210nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Department of Discovery Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50240283(CHEMBL4082930)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed