BDBM50241371 1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea::CHEMBL400314::N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide

SMILES CNC(=O)CNC(=O)Nc1nnc(S)s1

InChI Key InChIKey=YZJVCXDOAAOGHA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241371   

Target72 kDa type IV collagenase(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50241371(1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dih...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human Matrix metalloproteinase-2 (gelatinase-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50241371(1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dih...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241371(1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dih...)
Affinity DataKi:  1.66E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241371(1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dih...)
Affinity DataKi:  1.66E+5nMAssay Description:Inhibition of human stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241371(1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dih...)
Affinity DataKi:  1.66E+5nMAssay Description:Binding affinity for matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed