BDBM50241377 (S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea::(S)-3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide::3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide::CHEMBL251901

SMILES CNC(=O)[C@H](CO)NC(=O)Nc1nnc(S)s1

InChI Key InChIKey=LONXPMRZFFZWDV-VKHMYHEASA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241377   

TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241377((S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)...)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241377((S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)...)
Affinity DataKi:  3.10E+4nMAssay Description:Binding affinity for matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50241377((S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of human stromelysin-1 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50241377((S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human Matrix metalloproteinase-2 (gelatinase-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia and Upjohn

Curated by ChEMBL
LigandPNGBDBM50241377((S)-1-(3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)...)
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity for matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed