BDBM50242223 CHEMBL4091800

SMILES CCCCCC[C@H]1[C@@H](OC1=O)C(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)OCc1ccccc1

InChI Key InChIKey=QTYRAQXICRIBLH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50242223   

TargetProteasome subunit beta type-5(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50242223(CHEMBL4091800)
Affinity DataIC50: 370nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50242223(CHEMBL4091800)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50242223(CHEMBL4091800)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Boc-Leu-Arg-Arg-AMC substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Baylor University

Curated by ChEMBL
LigandPNGBDBM50242223(CHEMBL4091800)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMed