BDBM50242822 1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(2-fluorophenyl)thiophen-2-yl)urea::CHEMBL2070698::CHEMBL459631
SMILES NC(=O)Nc1sc(cc1C(=O)N[C@H]1CCCNC1)-c1ccccc1F
InChI Key InChIKey=ZYITZPCUXXBBIN-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50242822
Affinity DataEC50: 1.06E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair