BDBM50242918 1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]-pyrimidin-6-yl]phenyl}-3-(2-fluoro-5-trifluoromethylphenyl)-urea::CHEMBL512839

SMILES Cn1cc(cn1)-c1ccn2c(N)c(cnc12)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1

InChI Key InChIKey=AOYIJCJRPUFKNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242918   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50242918(1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50242918(1-{4-[7-Amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed