BDBM50243015 (+)-1-{(1S)-2-Piperazin-1-yl-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrochloride::CHEMBL470482

SMILES OC1(CCCCC1)[C@H](CN1CCNCC1)c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=MRQDQHDPSBHAEH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243015   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243015((+)-1-{(1S)-2-Piperazin-1-yl-1-[3-(trifluoromethox...)
Affinity DataIC50: 140nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243015((+)-1-{(1S)-2-Piperazin-1-yl-1-[3-(trifluoromethox...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed